A Research Center on Nanomaterials and Energy
 
Prof. Marcotte's researches among the 10 most viewed Analyst's articles on end of 2013.
mercredi 12 février 2014
Categories : Researches / Information

The Analyst Blog web site has published a list of the 10 most consulted scientific articles, during the period October 2013 to December 2013, in the publication Analyst. An article of Pr. Isabelle Marcotte is part of this list.

This article is about the single-channel electrophysiology of cell-free expressed ion channels by direct incorporation in lipid bilayers .


Single-channel electrophysiology of cell-free expressed ion channels by direct incorporation in lipid bilayers


Abstract :
Single-channel electrophysiology with lipid bilayer systems requires ion channel expression, purification from cell culture, and reconstitution in proteoliposomes for delivery to a planar bilayer. Here we demonstrate that single-channel current measurements of the potassium channels KcsA and hERGS5–S6 can be obtained by direct insertion in interdroplet lipid bilayers from microliters of a cell-free expression medium.

Source : Analyst Blog
Article : Analyst article